Consequently we accept no responsibility in the broadest sense of the word for damage that may result from applications based upon this information. KG - Warranty The details given here are merely intended for information purposes and are in no way legally binding.
#SUPERTAB 11SD PARTICLE SIZE FREE#
(250 mg tablets / 9 mm flat bevel tooling: 0.5% mag stearate) Compaction Force (kN) Tablet Strenght (N) 200 125 175 100 150 75 50 8 10 12 14 16 SuperTab® 14SD SuperTab® 11SD Lactopress® Spray Dried 250 DFE Pharma direct compression products Product type Product name Product attributes and applications Spray-dried lactose Lactopress® Spray Dried Direct Compression Lactopress® Spray Dried 250 Direct Compression Lactopress® Spray Dried 260 Direct Compression, for further improved flowability SuperTab® 11SD Direct Compression SuperTab® 14SD Direct Compression, high compactability Granulated lactose Lactopress® Granulated Direct Compression, good all round performance SuperTab® 30GR Direct Compression, good all round performance Anhydrous lactose Lactopress® Anhydrous Direct Compression Lactopress® Anhydrous 250 Direct Compression, dry granulation, encapsulation SuperTab® 21AN Direct Compression, dry granulation, encapsulation SuperTab® 22AN Direct Compression, free flowing grade Head Office Klever Strasse 187 P.O. The improvement in tablet strength may be useful for formulations that require extra compactability or the lower compaction forces required to achieve a given tablet strength can result in reduced tooling wear. This is a result of the optimisation of both the particle size of the crystalline component and the level of amorphous lactose. Comparative compaction SuperTab® 14SD is designed to have better compaction properties than for example SuperTab® 11SD and Lactopress® Spray Dried 250. In the USP-NF they fall into the category of lactose monohydrate “modified”. Eur., USP-NF and JP for lactose monohydrate. SuperTab® and Lactopress® Spray Dried products comply with the requirements of the Ph. Lactopress® Spray Dried products are all made in Borculo, the Netherlands. Both SuperTab® 11SD and 14SD are made in a dedicated pharmaceutical lactose plant in Nörten-Hardenberg, Germany, and SuperTab® 11SD is additionally made in Kapuni, New Zealand. Application notes Spray-dried lactose SuperTab® and Lactopress® are DFE Pharma’s brand names for direct compression lactose. The amorphous lactose content and the small individual crystals within the granule are important in conferring the good compaction properties of spray-dried lactose. The spherical shape and narrow particle size distribution confer the excellent flow properties of spray- dried lactose. The typical spherical granules consist of finely milled α -lactose monohydrate in a matrix of amorphous lactose. Lactose Morphology The morphology of spray-dried lactose is shown in the micrograph.
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